Thorne 5-MTHF 1 mg Active Methylfolate 60 Capsules
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Everything to know before you order
Support Your Body's Most Essential Processes with Thorne 5-MTHF — Active, Tissue-Ready Folate That Works from the First Capsule Folate is one of the most critical B vitamins your body depends on — but not all folate is created equal. Thorne 5-MTHF 1 mg delivers L-5-Methyltetrahydrofolate, the active, tissue-ready form of folate that your cells...
Full product description
Support Your Body's Most Essential Processes with Thorne 5-MTHF — Active, Tissue-Ready Folate That Works from the First Capsule
Folate is one of the most critical B vitamins your body depends on — but not all folate is created equal. Thorne 5-MTHF 1 mg delivers L-5-Methyltetrahydrofolate, the active, tissue-ready form of folate that your cells can use immediately, without requiring enzymatic conversion. For the millions of people with MTHFR gene variations who struggle to convert synthetic folic acid into usable folate, this distinction is everything. Whether you're exploring our Vitamins & Supplements - Nutritional Support & Wellness collection, stocking up through Health Essentials – OTC, First Aid & Personal Wellness, or catching a deal in Deals & Price Drops, this is a premium Thorne product at a price below what you'd pay anywhere else.
Thorne is one of the most trusted names in professional-grade supplementation — used and recommended by healthcare practitioners, athletes, and wellness-focused individuals worldwide. Their 5-MTHF formula uses Extrafolate-S®, a patented, highly bioavailable form of L-5-methyltetrahydrofolate from Gnosis S.p.A., encapsulated in a small, easy-to-swallow vegetarian hypromellose capsule. This bottle contains 60 capsules, sealed and new, with an expiration date of 02-2028. It ships from my hands in Burlington, Kentucky — inspected, photographed, and packed with care.
Features & Benefits
- Active, tissue-ready L-5-methyltetrahydrofolate bypasses MTHFR genetic conversion hurdles — no enzymatic conversion required
- Supports essential methylation cycles critical for cardiovascular health, brain function, bone health, and nerve cell integrity
- Promotes healthy production of key neurotransmitters including serotonin, dopamine, and melatonin
- Ideal dietary support for preconception health and healthy fetal brain and spinal cord development during pregnancy
- Free from gluten, soy, dairy, and artificial flavors
- Encapsulated in small, easy-to-swallow vegetarian hypromellose capsules
- Uses Extrafolate-S® — a patented, highly bioavailable methylfolate form from Gnosis S.p.A.
- Manufactured in an NSF Certified facility following cGMP standards
- Made in the USA from global ingredients
- New, sealed bottle — expiration 02-2028
What's Included
- 1 x Bottle of Thorne 5-MTHF 1 mg Methylfolate Supplement (60 Vegetarian Capsules)
- Original safety-sealed bottle included
Product Details
- Brand: Thorne
- Manufacturer: Thorne Research, Inc.
- Product Line: Active Folate / Methylation Support Series
- Model / SKU: B129
- UPC / GTIN: 693749129011
- Count: 60 Vegetarian Capsules
- Serving Size: 1 Capsule
- Servings Per Container: 60
- Recommended Age: Adult
- Route: Oral
- Country of Origin: USA (Made in the USA from global ingredients)
- Expiration Date: 02-2028 (Lot: 416196)
- Condition: New — Original safety-sealed bottle, never opened
Supplement Facts
Serving Size: 1 Capsule
Servings Per Container: 60
- Folate: 1.7 mg DFE (425% DV) — as 1 mg L-5-Methyltetrahydrofolate from L-5-Methyltetrahydrofolic Acid, Glucosamine Salt (Extrafolate-S®)
Extrafolate-S® is a registered trademark of Gnosis S.p.A.
Ingredients
Active Ingredient: L-5-Methyltetrahydrofolate (as L-5-Methyltetrahydrofolic Acid, Glucosamine Salt / Extrafolate-S®) — 1 mg per capsule
Other Ingredients: Microcrystalline Cellulose, Hypromellose (cellulose capsule), Leucine, Silicon Dioxide
Allergen Information
- Gluten-Free
- Soy-Free
- Dairy-Free
- Artificial Flavors Free
- No allergens listed on packaging
Directions
Take 1 capsule one to three times daily or as recommended by your health-care practitioner.
Storage Instructions
Keep tightly sealed in a cool, dry place.
Safety Note & Condition Notes
This bottle is brand new and safety-sealed. The expiration date stamped on the bottom of the bottle is 02-2028 (Lot: 416196). Keep out of reach of children. If you are pregnant, nursing, or taking medications, consult your healthcare practitioner before use.
†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Compliance & Certifications
- NSF Certified Facility Standard
- Gluten-Free Certified
- cGMP Compliant (Current Good Manufacturing Practices)
- FDA Disclaimer: †These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Pricing
- My Price: $22.49
- MSRP / Amazon / Thorne.com: $24.00
- Your Savings: $1.51 (6.3% OFF)
SKU / Barcode / MPN
- SKU / MPN: B129
- UPC / Barcode: 693749129011
- Lot Number: 416196
- Expiration: 02-2028
Limited Liquidation Release
This is a brand-new, factory-sealed bottle sourced through verified retail liquidation channels — not a return, not a damaged unit, and not a mystery lot. I only carry genuine, first-quality merchandise. Quantities are extremely limited and there will be no restock once this unit sells. If you've been looking for Thorne 5-MTHF at a better price, this is your window.
Shipping
I ship every order myself from Burlington, Kentucky using USPS Ground Advantage. Orders placed before 7 PM EST ship the next business day. Delivery is 2–5 business days, free, contiguous U.S. only. I photograph every shipment with its matching USPS tracking label for quality assurance.
Shipping Damage Policy
Every order ships via USPS Ground Advantage with insurance. I photograph every item before it leaves my hands — so there is a documented record of condition at the time of shipment. If your item arrives damaged, you file the USPS insurance claim directly. I provide all pre-shipment documentation to support your claim. I am not responsible for damage that occurs after confirmed delivery. No replacements are issued for post-delivery damage.
The More4less Outlet Promise
- One real product photo guaranteed — what you see is what ships.
- Lifestyle images are AI-generated for visual context only.
- 100% on-site Kentucky stock — every item is physically here at my location.
- No drop-shipping. Ever.
- I personally inspect every item for condition and packaging integrity before it is packed.
- I only sell brand-new liquidation deals sourced from verified retail channels — never returns, pallets, or mystery boxes.
- Orders placed before 7 PM EST (Mon–Fri) ship the next business day via USPS Ground Advantage — insured, trackable, and always free.
Support a Small Business
More4less Outlet is a one-person operation — and that one person is me, Chad. I pack your order, I answer your messages, I update inventory, and I keep prices low by doing everything myself. There is no warehouse team, no customer service department, no corporate escalation chain. When you shop here, you are not a transaction. You are a customer I actually remember. Every order genuinely helps me keep this small business running.
Leave a Tip at Checkout
If this listing helped you find what you were looking for — or you just want to show some love to a tiny one-person business — there is an optional tip field at checkout. It is never expected, always appreciated, and goes directly toward keeping the lights on and the shelves stocked. Thank you either way.
Frequently Asked Questions
What is 5-MTHF and how is it different from standard folic acid?
5-MTHF (L-5-Methyltetrahydrofolate) is the active, tissue-ready form of folate utilized directly by the body. Unlike synthetic folic acid, it does not require enzymatic conversion, making it especially beneficial for individuals with genetic MTHFR variations.
What are the key benefits of taking Thorne 5-MTHF 1 mg?
5-MTHF supports healthy methylation, cardiovascular function, neurotransmitter production (serotonin, dopamine, melatonin), nerve health, and healthy fetal brain and spinal cord development during pregnancy.
How many capsules should I take daily?
According to the product label, take 1 capsule one to three times daily, or as recommended by your healthcare practitioner.
Is Thorne 5-MTHF gluten-free?
Yes, Thorne 5-MTHF 1 mg is gluten-free, soy-free, and dairy-free, housed in a hypromellose vegetarian capsule.
Legal Notice
More4less Outlet sells authentic, brand-new products acquired through lawful liquidation channels under the First Sale Doctrine (17 U.S.C. § 109). More4less Outlet is not affiliated with, endorsed by, or sponsored by Thorne or Thorne Research, Inc. All brand names, trademarks, and product names are the property of their respective owners and are used solely for identification purposes.
Shipping & tracking
U.S. shipping is free and tracking is included. Orders are processed according to my published shipping schedule.
Read the shipping policyReturns & order concerns
Review the item-specific condition and packaging information before ordering. If an order concern arises, contact More4less Outlet promptly so the order record can be reviewed.
Read the return policyAuthenticity & reseller disclosure
More4less Outlet is an independent reseller and is not affiliated with or endorsed by the manufacturer unless expressly stated. Brand names and trademarks belong to their respective owners.
Limited availability: only 3 currently in stock. Inventory is held by More4less Outlet and may not be replenished.