Thorne 5-MTHF 5 mg Methylfolate - 60 Capsules

Deliver Bioactive Folate Directly Where Your Body Needs It Most

Deliver bioactive folate directly where your body needs it most. Thorne 5-MTHF 5 mg provides L-5-Methyltetrahydrofolate — the active, body-ready form of folate — at a clinical 5 mg potency per capsule. Unlike standard folic acid, which requires enzymatic conversion that many individuals cannot perform efficiently due to MTHFR gene variants, 5-MTHF is immediately bioavailable and ready for use in methylation, neurotransmitter synthesis, and cellular repair. Whether you're building a complete wellness stack from my Vitamins & Supplements collection, exploring clinical-grade essentials in Health Essentials, or catching a rare Thorne deal in my Deals & Price Drops — this is a standout find at a liquidation price.

Why You'll Love It

• Bioactive & Immediately Usable: Provides L-5-Methyltetrahydrofolate — the active form of folate that bypasses the conversion step required by standard folic acid, making it effective even for those with MTHFR gene variants.
• Clinical 5 mg Potency: Each capsule delivers 5,000 mcg (5 mg) of active methylfolate — a high-potency dose trusted by healthcare practitioners for targeted folate support.
• Methylation & Brain Support: Supports healthy methylation pathways critical for neurotransmitter production, mood regulation, cognitive function, and DNA synthesis.
• Prenatal Folate Support: Folate is essential for healthy fetal neural tube development — this bioactive form is preferred by many prenatal healthcare practitioners.
• Pure Thorne Formula: Uses Gnosis S.p.A.’s premium L-5-Methyltetrahydrofolate — a pharmaceutical-grade ingredient source trusted by clinical practitioners worldwide.

What's Included

• 1x Thorne 5-MTHF 5 mg Methylfolate — 60 Capsules (new, sealed)
• 60 servings per bottle (1 capsule per serving)
• Expiration: 02/2028 | Lot Number: 04.05400

Product Details

Supplement Facts

Ingredients

Active Ingredient: Folate 5,000 mcg DFE (5 mg) as L-5-Methyltetrahydrofolate, Calcium Salt — sourced from Gnosis S.p.A.
Other Ingredients: Listed on product label. Thorne formulas are free from gluten, dairy, soy, yeast, and artificial preservatives. Full ingredient list is printed on the bottle.

Allergen Information

Thorne 5-MTHF is formulated without gluten, dairy, soy, yeast, or artificial preservatives. If you have known allergies or sensitivities, review the full ingredient list on the bottle and consult your healthcare provider before use.

Directions / Instructions

Take 1 capsule daily, or as recommended by your healthcare practitioner. Do not exceed the recommended dose without professional guidance. Consult a licensed healthcare practitioner before use, especially if pregnant or nursing.

Storage Instructions

Store in a cool, dry place away from direct sunlight and moisture. Keep out of reach of children. Do not use if the tamper-evident seal is broken or missing.

Safety Note / Condition Notes

This bottle is new and sealed with an expiration date of 02/2028 (Lot #04.05400). Important: Folate supplementation during pregnancy should only be undertaken under the guidance of a licensed healthcare practitioner. High-dose folate (5 mg) is a clinical-strength dose — consult your doctor before use, particularly if you are pregnant, nursing, or managing a diagnosed MTHFR variant. Not intended to diagnose, treat, cure, or prevent any disease.

Compliance & Certifications

• Uses Gnosis S.p.A. pharmaceutical-grade L-5-Methyltetrahydrofolate
• Gluten-free, dairy-free, soy-free formula
• Manufactured in the USA in NSF-certified facilities
• Trusted by medical practitioners and integrative health professionals worldwide

Pricing

Sale Price: $50.99 | Original Retail: $60.00 | You Save: $9.01 (15% off)

SKU / Barcode / MPN

• SKU / MPN: B132 / LB13210
• UPC / Barcode: 693749132011
• Lot Number: 04.05400

Limited Liquidation Release

This is a brand-new, sealed bottle of Thorne 5-MTHF 5 mg sourced directly from verified retail liquidation channels — not a return, not a mystery pallet. Thorne supplements rarely hit the secondary market at a discount. The expiration is 02/2028, giving you a full 60-serving supply window. Limited quantity — no restock once it's gone.

Shipping

I ship every order myself from Burlington, Kentucky using USPS Ground Advantage. Orders placed before 7 PM EST ship the same business day. Orders placed after cutoff ship the next business day. Delivery is 2–5 business days, free, contiguous U.S. only. I photograph every shipment with its matching USPS tracking label for quality assurance.

Shipping Damage Policy

Every order ships via USPS Ground Advantage with insurance. I photograph every item before it leaves my hands — so there is a documented record of condition at the time of shipment. If your item arrives damaged, you file the USPS insurance claim directly. I provide all pre-shipment documentation to support your claim. I am not responsible for damage that occurs after confirmed delivery. No replacements are issued for post-delivery damage.

The More4less Outlet Promise

• One real product photo guaranteed — what you see is what ships.
• Lifestyle images are AI-generated for visual context only.
• 100% on-site Kentucky stock — every item is physically here at my location.
• No drop-shipping. Ever.
• I personally inspect every item for condition and packaging integrity before it is packed.
• I only sell brand-new liquidation deals sourced from verified retail channels — never returns, pallets, or mystery boxes.
• Orders placed before 7 PM EST (Mon–Fri) ship same day via USPS Ground Advantage — insured, trackable, and always free.

Support a Small Business

More4less Outlet is a one-person operation — and that one person is me, Chad. I pack your order, I answer your messages, I update inventory, and I keep prices low by doing everything myself. There is no warehouse team, no customer service department, no corporate escalation chain. When you shop here, you are not a transaction. You are a customer I actually remember. Every order genuinely helps me keep this small business running.

Leave a Tip at Checkout

If this listing helped you find what you were looking for — or you just want to show some love to a tiny one-person business — there is an optional tip field at checkout. It is never expected, always appreciated, and goes directly toward keeping the lights on and the shelves stocked. Thank you either way.

Frequently Asked Questions

Q: What is the difference between 5-MTHF and regular folic acid?
A: Standard folic acid is a synthetic form of folate that must be converted by the body into its active form (5-MTHF) through a multi-step enzymatic process. Individuals with MTHFR gene variants may have reduced ability to perform this conversion efficiently. Thorne 5-MTHF provides the active, bioavailable form directly — bypassing the conversion step entirely.

Q: What is the MTHFR gene variant and why does it matter?
A: MTHFR (methylenetetrahydrofolate reductase) is an enzyme involved in folate metabolism. Common variants in the MTHFR gene can reduce the body's ability to convert folic acid into active methylfolate. Supplementing with 5-MTHF directly supports methylation pathways regardless of MTHFR status.

Q: Is this safe to take during pregnancy?
A: Folate is essential for healthy fetal neural tube development. However, this is a clinical-strength 5 mg dose — significantly higher than standard prenatal folate amounts. Always consult your OB-GYN or licensed healthcare practitioner before taking high-dose folate during pregnancy.

Q: Is this product new and sealed?
A: Yes. This bottle is brand-new, factory-sealed, sourced from verified retail liquidation. The tamper-evident seal is intact and the expiration date is 02/2028 (Lot #04.05400).

Q: What is Gnosis S.p.A. and why does it matter?
A: Gnosis S.p.A. is an Italian pharmaceutical ingredient manufacturer recognized as a global leader in the production of high-purity L-5-Methyltetrahydrofolate. Thorne uses Gnosis-sourced methylfolate to ensure consistent potency and pharmaceutical-grade quality in every capsule.

Legal Notice

More4less Outlet sells authentic, brand-new products acquired through lawful liquidation channels under the First Sale Doctrine (17 U.S.C. § 109). More4less Outlet is not affiliated with, endorsed by, or sponsored by Thorne or Thorne Research. All brand names, trademarks, and product names are the property of their respective owners and are used solely for identification purposes.